![]() A vast amount of literature is available, often of low quality, making navigation hard, and adequate recommendation to those who ask for advice remain very challenging. Despite this being partially false, given the many adverse events that may derive from natural compounds ingestion, it is indeed true that many of the currently commercialized dietary supplements are virtually devoid of major side effects.Ĭurrently available food supplements feature several purported mechanisms of action, such as improvement of carbohydrate metabolism, increased lipolysis or energy expenditure, and reduced hunger. So-called super foods and food supplements have gained much popularity in recent years, for the generalized perception that natural substances may be synonym of health and balance. However, despite leading to improvement in many cases, the major issue is the presence of adverse events and reduced compliance. ![]() Most of these are safe, although some have risen concern. Several strategies have been proposed for the treatment of weight excess and its detrimental consequences, ranging from dietary regimens, to pharmacological treatments, physical exercise, and psychological approaches. The prevalence of obesity has been rising steadily for the past decades all over the world leading to an increase in prevalence of many complications of weight excess, some of which are well acknowledged, such as Type 2 Diabetes (T2D), obstructive sleep apnea syndrome (OSAS), non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease, while others are emerging and currently being investigated.
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